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To reach 350 skill in poison making, you need to learn 543 recipes. The various series of game-wide dropped leaves and vendor-sold venoms, levels 15 (rank I) through 106 (rank XIX), can get you there, thanks to the additional rank of XIX recipes with the RoS expansion. These series were introduced as a rogue poison revamp in April 2009, midway through the Seeds of Destruction expansion.
For the dropped leaves, I hope you have been collecting and saving them. You will need a minimum of about 6 of every different type (7 types) and level (up to 13 ranks), except for the lowest level of leaf, "Dry" (level 45), which you need 15 of each. Plus at least 1 each of all the different dropped Nigriventer Venoms and Gormar Venoms.
For vendor supplies, in addition to PoK, you will also need to visit Argath and Shard's Landing and/or The Overthere (RoS).
Note: To make the Consigned Bite of the Shissar recipes, you will need a Coffin Poison Bottle, which comes from the Grandmaster Assassin's Seal, which is quested.
Poison recipes from game-wide leaves and venoms:
19 Bite of the Shissar I - XIX
19 Consigned Bite of the Shissar I - XIX
32 Caladium Extract
21 Delphinium Extract
32 Laburnum Extract
32 Larkspur Extract
32 Muscimol Extract
32 Oleander Extract
18 Privit Extract
19 Anger of the Shissar I - XIX
9 Archer's Bane XI - XIX
19 E`ci's Lament I - XIX
16 Fighter's Bane IV - XIX
19 Gelidran Lament I - XIX
19 Hate of the Shissar I - XIX
19 Messenger's Bane I - XIX
10 Monk's Bane X - XIX
19 Myrmidon's Sloth I - XIX
19 Pyrilen Burn I - XIX
19 Quellious' Trauma I - XIX
19 Scorpion's Agony I - XIX
19 Solusek's Burn I - XIX
19 Spider's Bite I - XIX
19 Strike of Ssraeshza I - XIX
19 Strike of the Shissar I - XIX
16 Warlord's Bane IV - XIX
6 Tallon's Tactic XIV - XIX
6 Vallon's Tactic XIV - XIX
3 Hero's Toxin I - III
subtotal 550
Additional poison recipes:
6 freebie Abysmal Sea and Crescent Reach tasks (Simple)
4 freebie Abysmal Sea and Crescent Reach turn-ins (Simple)
1 scribe book: Poison Maker's Scrawl
5 scribe book: Peaceful Seas
1 Grandmaster Assassin's Vial
1 Toxicologist Ceramic Clay
42(+?) miscellaneous old world, PoP, OoW
total 610
For the dropped leaves, I hope you have been collecting and saving them. You will need a minimum of about 6 of every different type (7 types) and level (up to 13 ranks), except for the lowest level of leaf, "Dry" (level 45), which you need 15 of each. Plus at least 1 each of all the different dropped Nigriventer Venoms and Gormar Venoms.
For vendor supplies, in addition to PoK, you will also need to visit Argath and Shard's Landing and/or The Overthere (RoS).
Note: To make the Consigned Bite of the Shissar recipes, you will need a Coffin Poison Bottle, which comes from the Grandmaster Assassin's Seal, which is quested.
Poison recipes from game-wide leaves and venoms:
19 Bite of the Shissar I - XIX
19 Consigned Bite of the Shissar I - XIX
32 Caladium Extract
21 Delphinium Extract
32 Laburnum Extract
32 Larkspur Extract
32 Muscimol Extract
32 Oleander Extract
18 Privit Extract
19 Anger of the Shissar I - XIX
9 Archer's Bane XI - XIX
19 E`ci's Lament I - XIX
16 Fighter's Bane IV - XIX
19 Gelidran Lament I - XIX
19 Hate of the Shissar I - XIX
19 Messenger's Bane I - XIX
10 Monk's Bane X - XIX
19 Myrmidon's Sloth I - XIX
19 Pyrilen Burn I - XIX
19 Quellious' Trauma I - XIX
19 Scorpion's Agony I - XIX
19 Solusek's Burn I - XIX
19 Spider's Bite I - XIX
19 Strike of Ssraeshza I - XIX
19 Strike of the Shissar I - XIX
16 Warlord's Bane IV - XIX
6 Tallon's Tactic XIV - XIX
6 Vallon's Tactic XIV - XIX
3 Hero's Toxin I - III
subtotal 550
Additional poison recipes:
6 freebie Abysmal Sea and Crescent Reach tasks (Simple)
4 freebie Abysmal Sea and Crescent Reach turn-ins (Simple)
1 scribe book: Poison Maker's Scrawl
5 scribe book: Peaceful Seas
1 Grandmaster Assassin's Vial
1 Toxicologist Ceramic Clay
42(+?) miscellaneous old world, PoP, OoW
total 610